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Index > Protein center > Htr2a(Gene name) > Rat
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  • Htr2a (Gene name),
  • 5-hydroxytryptamine receptor 2A (Protein name ),  5HT2A_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Htr2a(Htr2);
    Protein name:
    5-hydroxytryptamine receptor 2A(5-HT-2;5-HT-2A);
    Alternative:
    Serotonin receptor 2A;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with MPDZ and INADL. May interact with MPP3, PRDX6, DLG4, DLG1, CASK, APBA1 and MAGI2.
    Function:
    This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein Localizes to the post-synaptic thickening of axo-dendritic synapses.
    Protein Attributes:
    Sequence length:
    471
    Sequence:
    50:
    MEILCEDNIS | LSSIPNSLMQ | LGDGPRLYHN | DFNSRDANTS | EASNWTIDAE | 
    100:
    NRTNLSCEGY | LPPTCLSILH | LQEKNWSALL | TTVVIILTIA | GNILVIMAVS | 
    150:
    LEKKLQNATN | YFLMSLAIAD | MLLGFLVMPV | SMLTILYGYR | WPLPSKLCAI | 
    200:
    WIYLDVLFST | ASIMHLCAIS | LDRYVAIQNP | IHHSRFNSRT | KAFLKIIAVW | 
    250:
    TISVGISMPI | PVFGLQDDSK | VFKEGSCLLA | DDNFVLIGSF | VAFFIPLTIM | 
    300:
    VITYFLTIKS | LQKEATLCVS | DLSTRAKLAS | FSFLPQSSLS | SEKLFQRSIH | 
    350:
    REPGSYAGRR | TMQSISNEQK | ACKVLGIVFF | LFVVMWCPFF | ITNIMAVICK | 
    400:
    ESCNENVIGA | LLNVFVWIGY | LSSAVNPLVY | TLFNKTYRSA | FSRYIQCQYK | 
    450:
    ENRKPLQLIL | VNTIPALAYK | SSQLQVGQKK | NSQEDAEQTV | DDCSMVTLGK | 
    471:
    QQSEENCTDN | IETVNEKVSC | V
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat 5-HT-2
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    E10283h
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    ELISA Kit for Rat 5-HT-2
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    E10283r
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    ELISA Kit for Rat 5-HT-2
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    E10283d
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    ELISA Kit for Rat 5-HT-2
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    E10283m
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    ELISA Kit for Rat 5-HT-2
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    E10283p
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    96T
    ELISA Kit for Rat 5-HT-2
    Cat.:
    E10283b
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    Packing:
    96T
    CLIA Kit for Rat 5-HT-2
    Cat.:
    U10283p
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    Packing:
    96T
    CLIA Kit for Rat 5-HT-2
    Cat.:
    U10283r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat 5-HT-2
    Cat.:
    U10283h
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat 5-HT-2
    Cat.:
    U10283b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat 5-HT-2
    Cat.:
    U10283d
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    Packing:
    96T
    CLIA Kit for Rat 5-HT-2
    Cat.:
    U10283m
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Rat 5-HT-2
    Polyclonal Antibody for Rat 5-HT-2
    Cat.:
    P10283Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat 5-HT-2
    Polyclonal Antibody for Rat 5-HT-2
    Cat.:
    P10283Rb-r
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    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat 5-HT-2
    Polyclonal Antibody for Rat 5-HT-2
    Cat.:
    P10283Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat 5-HT-2
    Monoclonal Antibody for Rat 5-HT-2
    Monoclonal Antibody for Rat 5-HT-2
    Monoclonal Antibody for Rat 5-HT-2
    Monoclonal Antibody for Rat 5-HT-2
    Monoclonal Antibody for Rat 5-HT-2
    Protein for Rat 5-HT-2
    Protein for Rat 5-HT-2
    Protein for Rat 5-HT-2
    Protein for Rat 5-HT-2
    Protein for Rat 5-HT-2
    Protein for Rat 5-HT-2

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    References
    1. 1.
      "The 5HT2 receptor defines a family of structurally distinct but functionally conserved serotonin receptors."
      Julius D. , Huang K.N. , Livelli T.J. , Axel R. , Jessell T.M.
      Proc. Natl. Acad. Sci. U.S.A.87:928-932(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    2. 2.
      "Structure and functional expression of cloned rat serotonin 5HT-2 receptor."
      Pritchett D.B. , Bach A.W.J. , Wozny M. , Taleb O. , Dal-Toso R. , Shih J.C. , Seeburg P.H.
      EMBO J.7:4135-4140(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION
    3. 3.
      "The 5-HT2 serotonin receptor gene Htr-2 is tightly linked to Es-10 on mouse chromosome 14."
      Liu J. , Chen Y. , Kozak C.A. , Yu L.
      Genomics11:231-234(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      "5-HT(2A) receptors: location and functional analysis in intestines of wild-type and 5-HT(2A) knockout mice."
      Fiorica-Howells E. , Hen R. , Gingrich J. , Li Z. , Gershon M.D.
      Am. J. Physiol.282:G877-G893(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY
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